Compile Data Set for Download or QSAR
maximum 50k data
Found 130 of ic50 data for polymerid = 50000704
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50029417(CHEMBL277363 | [4-(4-Methoxy-phenyl)-4H-benzo[b]py...)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50422202(CHEMBL24662)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50018796(2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataIC50:  2.60nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50336640((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50422200(CHEMBL278804)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50422196(CHEMBL25512)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50072809(4-[2-(4-Cyano-furazan-3-ylmethoxy)-phenyl]-2,6-dim...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317840(CHEMBL1099188 | diethyl 4-(2,3-difluorophenyl)-2,6...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317817(3-cyclohex-2-enyl 5-methyl 2,6-dimethyl-4-(3-nitro...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317813(3-ethyl 5-(2-(methacryloyloxy)ethyl)2,6-dimethyl-4...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317802(3-allyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317836(3-methyl 5-(3-phenoxypropyl)2,6-dimethyl-4-(3-nitr...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317833(3-methyl 5-(3-phenylbutyl)2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317835(3-(2-(benzyloxy)ethyl)5-methyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50422191(CHEMBL24998)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317804(3-allyl 5-ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317803(3-allyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50280077(CHEMBL18988 | sec-Butyl-[4-(2,4-dimethoxy-phenyl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317775(CHEMBL1099222 | diethyl 2,6-dimethyl-4-(2-(methylt...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317826(3-furan-2-ylmethyl 5-methyl 2,6-dimethyl-4-(3-nitr...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317815(3-benzyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317788(CHEMBL1094989 | diethyl 2-butyl-6-methyl-4-(3-nitr...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317821(3-(3,4-difluorobenzyl)5-methyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317807(3-cyclopropylmethyl 5-methyl 2,6-dimethyl-4-(3-nit...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317810(3-methyl 5-(2,2,2-trifluoroethyl)2,6-dimethyl-4-(3...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317809(3-(2-chloroethyl)5-methyl 2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317825(3-benzo[d][1,3]dioxol-5-ylmethyl 5-methyl 2,6-dime...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50422192(CHEMBL25278)
Affinity DataIC50:  22nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317827(3-methyl 5-thiophen-2-ylmethyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50072818(4-[2-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317820(3-(3-fluorobenzyl)5-methyl 2,6-dimethyl-4-(3-nitro...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50422203(CHEMBL284195)
Affinity DataIC50:  29nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50029414(Acetic acid 4-(4-methoxy-phenyl)-4H-benzo[b]pyrrol...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317822(3-methyl 5-(2,4,6-trichlorobenzyl)2,6-dimethyl-4-(...)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317776(CHEMBL1086836 | dimethyl 2,6-dimethyl-4-(2-(methyl...)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317805(3-but-3-ynyl 5-methyl 2,6-dimethyl-4-(3-nitropheny...)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317830(3-cinnamyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317794(CHEMBL1094740 | diethyl 2-(acetoxymethyl)-6-methyl...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317832(3-methyl 5-(4-phenylbutyl)2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317834(3-(4-(4-methoxyphenyl)butyl)5-methyl 2,6-dimethyl-...)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317831(3-(4-chlorophenethyl)5-methyl 2,6-dimethyl-4-(3-ni...)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50072811(2,6-Dimethyl-4-[2-(4-methyl-5-oxy-furazan-3-ylmeth...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317819(3-(3,5-dinitrobenzyl)5-methyl 2,6-dimethyl-4-(3-ni...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317828(3-(2,3-dihydro-1H-inden-2-yl)5-methyl 2,6-dimethyl...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317798(CHEMBL1098064 | diethyl 2-(2-cyanovinyl)-6-methyl-...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317792(CHEMBL1094405 | diethyl 2-(hydroxymethyl)-6-methyl...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50004704((+)-cis-Diltiazem | (2S,3S)-5-(2-(dimethylamino)et...)
Affinity DataIC50:  46nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317829(3-(2-(2-chlorophenoxy)ethyl)5-methyl 2,6-dimethyl-...)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50317806(3-methyl 5-(3-methylbut-3-enyl)2,6-dimethyl-4-(3-n...)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50029426(CHEMBL24675 | [2-(3,4-Dimethoxy-phenyl)-ethyl]-[4-...)
Affinity DataIC50:  52nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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